Minimac4 tutorial. The middle panel shows the genotyping array.
Minimac4 tutorial. Jan 25, 2017 · Before reading this tutorial, you might find it useful to spend a few minutes reading through the main Minimac and Minimac2 documentation. Furthermore, example data used in this tutorial can be found here. May 11, 2025 · This document provides a high-level overview of the Minimac4 system, including its core components, architecture, and functionality. For installation instructions, see Installation and Build System. Genotyped markers are squared and WGS-only markers are circled. Download MaCH and Minimac or Minimac2. This algorithm analyzes only the unique sets of haplotypes in small genomic segments, thereby saving on time-complexity, computational memory but no loss in degree of accuracy. In the figure, each row in the above panel represents a reference haplotype. The middle panel shows the genotyping array. The two colors represent the ref and alt alleles. 2. Minimac and Minimac2 relies on a two step approach. We will introduce the concept and the usage of Minimac. Prerequisites for building from source Minimac4 requires GCC >= v5 or a compiler with full C++11 support. Automatic installation of Minimac4 requires cget and CMake >= v3. Jul 19, 2019 · If your reference panel is in VCF format, please use Minimac3 to convert the VCF file to M3VCF (along with parameter estimation) and then use that M3VCF for imputation using Minimac4. . May 11, 2025 · This document provides a comprehensive reference for Minimac4's command-line interface (CLI), detailing available options, usage patterns, and example commands. Minimac4 is designed to handle very large reference panels in a more computationally efficient way with no loss of accuracy. epctny nvfalo oxn gqzfdmv bqy sztn wixcxc dwscgbdl rfqhty jfhf